| Choice | Drug | Dosage |
|---|---|---|
| Formulary choice | Alfacalcidol (1α–hydroxycholecalciferol) capsules 250nanograms, 500nanograms, 1microgram; oral drops 2micrograms/mL | Dose: Orally, initially 1microgram daily (elderly 500nanograms) adjusted to avoid hypercalcaemia; maintenance, usually 0.25-1microgram daily |
Prescribing Notes
- If hypercalcaemia occurs, alfacalcidol should be stopped and restarted when plasma calcium is normal (usually within a week).
- Supplemental calcium (usual dose 1-2g daily) may be required in addition to alfacalcidol. Care should be taken to avoid hypercalcaemia.