6.2.3.2 Hypoparathyroidism

ChoiceDrugDosage
Formulary choiceAlfacalcidol (1α–hydroxycholecalciferol) capsules 250nanograms, 500nanograms, 1microgram; oral drops 2micrograms/mLDose: Orally, initially 1microgram daily (elderly 500nanograms) adjusted to avoid hypercalcaemia; maintenance, usually 0.25-1microgram daily

Prescribing Notes

  • If hypercalcaemia occurs, alfacalcidol should be stopped and restarted when plasma calcium is normal (usually within a week).
  • Supplemental calcium (usual dose 1-2g daily) may be required in addition to alfacalcidol. Care should be taken to avoid hypercalcaemia.