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Home Formulary 13.0 Skin 13.10 Anti-infective skin preparations 13.10.1.2. Antibacterial preparations also used systemically

13.10.1.2. Antibacterial preparations also used systemically

ChoiceDrug
1st choice

Fusidic acid 2% cream
Sodium fusidate 2% ointment

Or
Metronidazole 0.75% cream/gel

Prescribing notes

  • To avoid the development of resistance, fusidic acid should only be used for localised infections and not be used for longer than 7 days.
  • For acute impetigo, refer to Primary Care Antibiotic Guidelines (note hydrogen peroxide 1% is first line for localized non-bullous impetigo)
  • Topical antibacterials should be avoided in leg ulcers unless used for short courses for defined infections; treatment of bacterial colonization is generally inappropriate
  • Metronidazole gel is helpful for secondary infections of fungating tumours

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