Generalised anxiety disorder (GAD), social anxiety disorder

1st choiceNon-pharmacological treatment
2nd choiceSertraline tablets 50mg, 100mg [unlicensed indication]Dose:
Initially 25mg (half a tablet) daily, increased if necessary by increments of 25mg at intervals of at least one week to max 200mg daily

Prescribing Notes

  • GAD should be distinguished from acute anxiety state. Treatment options include psychological, pharmacological and self-help approaches.
  • Benzodiazepines are effective for short–term treatment (2-4 weeks) of GAD but there is a risk of dependence, sedation, accidents and withdrawal symptoms. Antidepressants are preferred.
  • Refer to NICE GG 159 for the management of Social Anxiety Disorder.


See cautions here.