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2.8.2.2 Treatment of pulmonary embolism and deep vein thrombosis and prevention of recurrent

ChoiceDrug
1st choice

Apixaban tablets 2.5mg, 5mg

2nd choicesRivaroxaban 15mg, 20mg tablets
Or
Dabigatran capsules 110mg, 150mg
Or
Edoxaban 30mg, 60mg tablets
Or
Warfarin tablets 1mg, 3mg

Prescribing Notes

  • Refer to NICE guidance on anticoagulation treatment for venous thromboembolism (NICE make recommendations on preferred anticoagulant choices; these vary depending on co-morbidities/ clinical features. Apixaban is recommended first line in patients with no relevant co-morbidities or significant clinical features.)
  • Please note dosing schedule. A number of incidents have been reported where the initial twice daily dose for rivaroxaban was continued beyond the 21 days following discharge from hospital, presenting a significant risk to patients. This type of incident is also possible with apixaban. Refer to BNF.

Cautions

See here.