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Home Formulary 7.0 Contraception, Gynaecology and Urinary Tract Disorders 7.2 Treatment of vaginal and vulval conditions 7.2.1 Topical HRT for vaginal atrophy

7.2.1 Topical HRT for vaginal atrophy

ChoiceDrug
1st choiceEstriol 0.1% intravaginal cream
2nd choiceEstradiol 10microgram vaginal tablets

Prescribing Notes

  • Prescribe as per NICE NG23.
  • Offer vaginal oestrogen to women with urogenital atrophy (including those on systemic HRT) and continue treatment for as long as needed to relieve symptoms.
  • Consider patient preference and response when selecting the formulation of vaginal oestrogen e.g. cream or vaginal tablets.
  • For people with a personal history of breast cancer see NICE NG23.
  • Women using long-term vaginal oestrogen treatments do not need to add in cyclical progestogen.
  • For systemic HRT options see 6.4.1 

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